GAMBARAN EFEKTIVITAS EKSTRAK RIMPANG LENGKUAS MERAH ( Alpinia purpurata K. Schum) SEBAGAI ANTIBAKTERI TERHADAP Klebsiella pneumoniae

Lathifah, Anggraini (2020) GAMBARAN EFEKTIVITAS EKSTRAK RIMPANG LENGKUAS MERAH ( Alpinia purpurata K. Schum) SEBAGAI ANTIBAKTERI TERHADAP Klebsiella pneumoniae. Diploma thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Klebsiella pneumoniae is a bacterial stem, gram-negative, opportunistic pathogen, and causes nosocomial infections including pneumonia and urinary tract infections. Infections caused by K. pneumoniae can be treated with antibiotics, the high use of antibiotics incorrectly can cause antibiotic resistance. One of the natural ingredients that can be used as alternative medicine is the Alpinia purpurata K. Schum rhizome. Scientific Writing based on literature studies and literature review aims to determine the effectiveness of the Alpinia purpurata K. Schum rhizome extract as an antibacterial against K. pneumoniae. This research uses the literature study method. Data collection in this study uses secondary data taken from several scientific journals. Analysis of the data used is descriptive analysis. Research results from the three reviewed journals reviewed showed that all extract concentrations were able to form radical zones. The highest concentration of the three journals in a row showed the inhibition zone diameter of 9.6 mm (100%), 11.03 mm (80%) and 13 mm (80%), indicating that the higher the concentration given, the more radical zones are also formed. All extract concentrations were unable to form radical zones for the growth of K. pneumoniae equal or greater than the 5µg ciprofloxacin antibiotic, but were still able to be inhibited by the extract of the Alpinia purpurata K. Schum rhizome. This scientific paper can be concluded that the extract of the Alpinia purpurata K. Schum rhizome can inhibit the growth of K. pneumoniae, the higher the concentration given the greater the radical zones formed.

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