HUBUNGAN ANTARA HIGH SENSITIVE C-REACTIVE PROTEIN (HS-CRP) DENGAN HbA1c PADA PENDERITA DIABETES MELITUS TIPE2 DI KLINIK PRODIA PEKANBARU

Dina, Rahmi Effendi (2022) HUBUNGAN ANTARA HIGH SENSITIVE C-REACTIVE PROTEIN (HS-CRP) DENGAN HbA1c PADA PENDERITA DIABETES MELITUS TIPE2 DI KLINIK PRODIA PEKANBARU. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

The background of this study is that HbA1c is one of the tests to diagnose and control diabetes. The HbA1c examination is used to measure the average amount of hemoglobin A1c bound to blood sugar (glucose) over the last three months. Insulin resistance as a cause of type 2 diabetes mellitus is associated with a subclinical inflammatory process. Insulin resistance along with obesity, hypertension, and dyslipidemia contribute to the metabolic syndrome, a condition that is closely associated with an increased risk of cardiovascular disease. High sensitivity C reactive protein (hs-CRP) is an inflammatory marker that is thought to be associated with type 2 diabetes mellitus and cardiovascular disease. Many studies have found an association between hs-CRP and HbA1c as a marker of glycemic control in subjects with diabetes mellitus This research method is observational using a cross sectional approach. The subjects in this study were all patients at Prodia Pekanbaru Clinic who were diagnosed with type 2 diabetes mellitus. Research data The relationship between high sensitive c-reactive protein (hsCRP) and HbA1c in patients with type 2 diabetes mellitus at the Prodia Pekanbaru clinic will be processed through editing and coding processes using the SPSS statistical data processing application. Based on the results of data analysis and discussion that has been carried out in this study, it can be concluded that the research data is normally distributed if the normality test value is obtained, a significant value of 0.000, which means that the data is normally distributed and there is a statistically significant relationship between hs-CRP levels and HbA1c in patients with type 2 diabetes mellitus (p = 0.043).

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