PENGARUH FAKTOR USIA TERHADAP AKTIVITAS ENZIM CHOLINESTERASE SEBAGAI AKIBAT PAPARAN PESTISIDA PADA PETANI DESA GEMBLEGAN KABUPATEN KLATEN

Nunun, Sitoresmi (2022) PENGARUH FAKTOR USIA TERHADAP AKTIVITAS ENZIM CHOLINESTERASE SEBAGAI AKIBAT PAPARAN PESTISIDA PADA PETANI DESA GEMBLEGAN KABUPATEN KLATEN. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Farmers' activities in cultivating agricultural land cannot be separated from the use of pesticides to control plant pests. Pesticides have risks that harm the health of farmers and the surrounding environment. Pesticides enter the body through the respiratory tract and unprotected skin. Pesticide poisoning can cause a decrease in the activity of the cholinesterase enzyme in the blood which can cause death. The purpose of this study was to determine whether there was an influence of the age factor of the farmers with the activity of the Cholinesterase enzyme due to exposure to pesticides on farmers in Gemblegan Village, Klaten Regency. This type of research is analytic observational with random sampling technique. The study was conducted at the Clinical Laboratory of Prodia Surabaya by measuring the activity of the Cholinesterase enzyme using Roche Cobas c 501. This study used a cross sectional study design with a sample of 20 farmers. The sample is in the form of serum taken from the farmer's venous blood and stored in a vacuum tube without yellow anticoagulant then centrifuged to obtain serum. The variables of this study were age and activity of the Cholinesterase enzyme. The results of statistical tests with SPSS using Fisher's exact test obtained p value = 1,000, RP = 1,500 and 95% CI = 0.109-20,675, which shows that age has no correlation with Cholinesterase enzyme activity. There is no effect of age on Cholinesterase enzyme activity as a result of pesticide exposure to farmers in Gemblegan Village, Klaten Regency

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