UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% LIMBAH KULIT PISANG KEPOK (Musa paradisiaca L.) TERHADAP PERTUMBUHAN Salmonella typhi

Dina, Nurkumala Sari (2019) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% LIMBAH KULIT PISANG KEPOK (Musa paradisiaca L.) TERHADAP PERTUMBUHAN Salmonella typhi. Diploma thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Salmonella typhi is a bacteria that causes typhoid fever which is an acute endemic disease that occurs in the digestive tract. These organisms can enter through mouth, usually with contaminated food and beverages. Treatment of diseases caused by Salmonella typhi bacteria usually uses the Ciprofloxacin. The use of antibiotics can cause side effects. The skin of M. paradisiaca L. is a type of plant that can be used as a natural medicine. M. paradisiaca L. peel contains alkoloid compounds, flavonoids, saponins, tannins and which can inhibit bacterial growth. The purpose of this study was to determine the antibacterial activity of ethanol 96% extract of kepok banana peel (Musa paradisiaca L.) waste. This research included descriptive post test with control using maceration method as an antibacterial activity test and was carried out at the Laboratory Bacteriology of STIKES National from February - June 2019. The population in this study was kepok banana peel (Musa paradisiaca L.). The sampling technique in this study used Quta Sampling. The concentration of M. paradisiaca L. peel extract used was 20%, 40%, 60%, 80% and 100%. Based on the results of the study it was found that the M. paradisiaca L. peel inhibition zone on the growth of Salmonella typhi at a concentration of 20% was 6.03 mm, the concentration of 40% was 6.33 mm, the concentration of 60% was 6.78 mm, the concentration of 80% was 7, 33 mm and 100% concentration of 8.25% in the resistance limit because the inhibition zone was less than 15 mm. The conclusion of this study is that the ethanol extract 96% of M. paradisiaca L. peel is able to form a radical has the ability to inhibit the growth of Salmonella typhi bacteria. The inhibition zone produced by ethanol extract 96% of M. paradisiaca L. peel is smaller compared to positive control, namely Ciprofloxacin 5 μg with an average yield of 38.50 mm

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