PERBEDAAN KADAR ASAM URAT SEBELUM DAN SESUDAH PEMBERIAN JAMUR TIRAM PUTIH (Pleurotus ostreatus) PADA KADER PKK KELURAHAN DANUKUSUMAN

Novia, Wulandari (2020) PERBEDAAN KADAR ASAM URAT SEBELUM DAN SESUDAH PEMBERIAN JAMUR TIRAM PUTIH (Pleurotus ostreatus) PADA KADER PKK KELURAHAN DANUKUSUMAN. Diploma thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Joint pain is a disease that is often experienced as a person ages, where the body experiences a decrease in the musculoskeletal system which is characterized by pain in the joints. One of the joint pain can be caused by hyperuricemia. Hyperuricemia can be treated by giving Allopurinol. The use of Allopurinol continuously can cause side effects, so it is necessary to look for natural free antiradical types to reduce free radicals that can damage the human body, one of which is the White Oyster Mushroom (Pleurotus ostreatus). White Oyster Mushroom Polysaccharide (Pleurotus ostreatus) functions as an antioxidant, where this antioxidant can be used as a decrease in uric acid levels by inhibiting the xanthine oxidase enzyme mechanism. This study aims to determine the differences in uric acid levels before and after administration of white oyster mushroom (Pleurotus ostreatus) to PKK caders in Danukusuman village. The type of this research is Experimental Analytic with Pretest and Postest Without Control approaches. When the study was conducted in November to May 2020. The sample in this study were 30 people with the sampling technique used was purposive sampling. Data were analyzed using SPSS 18 for Windows. The hypothesis test used is the Paired T Test. The results of the research analysis showed significant results with a significance value ((p) = 0.000 ≤ 0.05). So it can be concluded "There is a significant difference between the levels of uric acid before and after giving of White Oyster Mushroom (Pleurotus ostreatus) to PKK Caders in Danukusuman Village"

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