PENGGUNAAN OBAT-OBATAN PENGINDUKSI HATI PADA PASIEN HEPATITIS RAWAT INAP DI RSIA RESTU IBU PERIODE 2017-2019

Mutiana, Mutiana (2020) PENGGUNAAN OBAT-OBATAN PENGINDUKSI HATI PADA PASIEN HEPATITIS RAWAT INAP DI RSIA RESTU IBU PERIODE 2017-2019. Diploma thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Hepatitis is a disease of the liver caused by a virus. The use of liverinducing drugs in hepatitis patients can increase the risk of liver damage. In the treatment of patients with hepatitis still found the administration of drugs that have hepatotoxic effects which are feared to worsen liver damage. This study aims to determine the characteristics of hepatitis patients, find the existence of hepatotoxic drugs in hepatitis patients and find out the percentage of hepatotoxic drugs. This research is a non-experimental study with a saturated sampling design and data analysis is done descriptively. Collecting data through patient drug use records on patient medical record sheets The total sample of this study was 105 patients. The results of this study indicate that of the 105 study subjects known 52 patients (50%) received liver-inducing drugs and the average percentage of liver-inducing drugs given to 52 patients were ceftriaxone (42%), paracetamol (26%), asam mefenamat (21%), cefotaxime (5%), ranitidine (4%) dan omeprazole (2%) The most widely used inducing drug is ceftriaxone with a percentage of 54%. Ceftriaxone causes cholestasis where the results of imperfect metabolism will crystallize and settle in the gall bladder, causing blockages that form gallbladder stones. Further research is needed on the effect of day-inducing drug administration on hepatitis patients based on parameters of liver function tests.

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