UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL UMBI BAWANG LANANG HITAM (Allium sativum L.) SECARA IN VITRO

Desty, Putri Pancawati (2021) UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL UMBI BAWANG LANANG HITAM (Allium sativum L.) SECARA IN VITRO. Diploma thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Diabetes mellitus is one of the most risky comorbid diseases and worsens the infected person COVID-19. Blood sugar control is very important to maintain the body's immune system. Natural medicine for anti-diabetes is more popular with the public. This research was conducted to determine the ethanol extract of black lanang onion tubers (Allium sativum L.) has the ability to reduce glucose levels by 50%. Black lanang onion tubers (Allium sativum L.) macerated with 70% ethanol. The results showed that black lanang onion tubers contained flavonoids, polyphenols and saponins. The study of antidiabetic activity used the Nelson-Somogy method using a UV-Vis spectrophotometer instrument with operating time after heating for 25 minutes and a wavelength of 746 nm. Measurement of the decrease in glucose levels using five concentrations of 1 ppm, 2 ppm, 3 ppm, 4 ppm, 5 ppm. The results showed ethanol extract of black lanang onion tubers (Allium sativum L.) has a very strong ability to reduce glucose levels with an EC value of 3.8790 ppm and %KV of 0.6368%.

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