POLA RESISTENSI BAKTERI Escherichia coli DAN Pseudomonas aeruginosa TERHADAP ANTIBIOTIK AMIKACIN DAN MEROPENEM PADA PASIEN DENGAN INFEKSI SALURAN KEMIH DI RSU ISLAM KLATEN

Sih, Sulasmi (2021) POLA RESISTENSI BAKTERI Escherichia coli DAN Pseudomonas aeruginosa TERHADAP ANTIBIOTIK AMIKACIN DAN MEROPENEM PADA PASIEN DENGAN INFEKSI SALURAN KEMIH DI RSU ISLAM KLATEN. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Urinary Tract Infections (UTIs) are the most common infections acquired in hospitals that result in significant morbidity. The pattern of bacterial resistance that causes UTI will play an important role in the success of UTI treatment. The variety of bacteria, including Escherichia coli and Pseudomonas aeruginosa, and the lack of clinical trials of antibiotics carried out make it difficult for doctors to choose drugs. The purpose of this study was to determine the trend of resistance of Escherichia coli and Pseudomonas aeruginosa bacteria to amikacin and meropenem antibiotics at the Klaten Islamic Hospital for the 2019-2020 period. The method of this research is descriptive retrospective sampling technique in this study is purpose sampling. period 2019-2020 The subject of this study on urinary tract infections with urine objects examined for sensitivity culture, a regression test was carried out to determine the level of the variable. The results of the study with a total of 144 cases, 75 cases caused by Escherichia coli and 69 cases caused by Pseudomonas aeruginosa and the results were processed by regression tests to determine the level of correlation between antibiotic use and bacterial resistance, Escherichia coli to amikacin and meropenem, the value of y = - ( negative) 0.0874 and R2 0.2376, Pseudomonas aeruginosa bacteria against amikacin values y = - (negative) 0.0378 and R2 0.0860 and Pseudomonas aeruginosa bacteria against meropenem values y = - (negative) 0.0874 and R2 0 ,2376 which means that there is a downward trend of bacterial resistance with weak data.

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