PENENTUAN KONSENTRASI HAMBAT MINIMUM (KHM) PERASAN LEMON (Citrus limon) TERHADAP PERTUMBUHAN JAMUR Candida albicans

Aswina, Nabil Listyani (2022) PENENTUAN KONSENTRASI HAMBAT MINIMUM (KHM) PERASAN LEMON (Citrus limon) TERHADAP PERTUMBUHAN JAMUR Candida albicans. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

	Text Fulltext Aswina Nabil Listyani.pdf Restricted to Repository staff only Download (2MB)
	Text Intisari&Abstract.pdf Download (185kB)

Abstract

Candida albicans is a normal microflora that is in the human oral cavity, human digestive tract, female genitalia and also on the skin in Indonesia. Alternative medicine is recently being chosen by the community because it is considered safer other than chemicals. The secondary metabolite compounds found in Lemon (Citrus limon) juice, such as flavonoids, alkaloids, saponins, and citric acid can act as antifungal agents. Antifungal resistance can occur due to excessive use of antifungals. Minimum Inhibitory Concentration (MIC) testing is one way to avoid antifungal resistance. This study aimed to determine the minimum inhibitory concentration (MIC) of lemon (Citrus limon) juice, which can provide an inhibition zone for the growth of Candida albicans. This study uses experimental research methods by conducting special experiments to prove something under conditions determined by the researcher. The results obtained from each treatment were concentrations of 25% (16.25 mm), 24% (12 mm), 23% (9 mm), 22% (Irradical 4 mm), 21% (Irradical 2.25 mm ), ketoconazole 2% positive control (26 mm), and aquadest negative control (0 mm). LSD (Least Significant Difference) post hoc test result showed that a each treatment had a significant difference in inhibitory power, except at concentration of 22% against 21% and vice versa, which had the same inhibitory power. Based on the results research, it can be seen that the minimum inhibitory concentration of lemon juice (Citrus limon) on the growth of Candida albicans is 23% with a radical zone diameter of 9 mm in the moderate inhibition category.

Actions (login required)

View Item