HUBUNGAN AKTIVITAS ENZIM CHOLINESTERASE BERDASARKAN MASA KERJA AKIBAT PAPARAN PESTISIDA PADA KELOMPOK TANI DESA GEMBLEGAN KABUPATEN KLATEN

Didik, Supriyadi (2022) HUBUNGAN AKTIVITAS ENZIM CHOLINESTERASE BERDASARKAN MASA KERJA AKIBAT PAPARAN PESTISIDA PADA KELOMPOK TANI DESA GEMBLEGAN KABUPATEN KLATEN. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

The use of pesticides to control plant pests has a detrimental impact on the health of farmers and the environment. Pesticides enter the body through the respiratory tract and unprotected skin. Pesticide poisoning causes a decrease in the activity of the cholinesterase enzyme in the blood. The purpose of this study was to determine whether there was a relationship between the activity of the cholinesterase enzyme based on the working period of the farmer group in Gumblegan Village, Klaten Regency. This type of research is analytic observational with random sampling technique. Measurement of cholinesterase enzyme activity using Roche Cobas c501. This study used a cross sectional study design with a sample of 20 farmers. Samples were taken from the farmer's venous blood and stored in a vacuum tube without yellow anticoagulant then centrifuged to collect serum. The variables of this study were the working period and the activity of the cholinesterase enzyme. The results of statistical tests with SPSS using Fisher's exact test obtained p value = 1,000, RP = 0.667 and 95% CI = 0.048-9.189. There is no relationship between the activity of the Cholinesterase enzyme and the working period of farmers in Gumblegan Village, Klaten Regency in 2022.

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