PENGARUH PEMBERIAN EKSTRAK ETANOL SIMPLISIA PEGAGAN (Centella asiatica (L.) Urban) SEBAGAI ANTIJAMUR TERHADAP PERTUMBUHAN Candida albicans

Nourma, Priska Dianggi Tamba (2022) PENGARUH PEMBERIAN EKSTRAK ETANOL SIMPLISIA PEGAGAN (Centella asiatica (L.) Urban) SEBAGAI ANTIJAMUR TERHADAP PERTUMBUHAN Candida albicans. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Candidiasis is a common fungal infection in Indonesia. Some examples of chemical antifungal drugs include those from the azole group such as ketoconazole, but these antifungal drugs have weaknesses. Therefore, several previous researchers have found another alternative that has the potential to be a natural antifungal, namely (Centella asiatica (L.) Urban). The purpose of this study was to prove the antifungal activity of the ethanol extract of pegagan simplicia on the growth of Candida albicans. The study was using an experimental method with concentration variations of 5%, 10%, 15%, 20% and 25% on each ethanol extract of pegagan simplicia. In this study, diffusion disk Kirby-Bauer was use and Ketoconazole 2% antifungal was use as a positive control and 10% DMSO as a negative control. Data analysis in this study was analyze qualitatively, by processing data and analyzing factors related to research by presenting data in the form of words, sentences, and pictures. In this study, it was found that the ethanolic extract of pegagan simplicia did not form an inhibition zone for the growth of Candida albicans.

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