PENGARUH PEMBERIAN BUBUK KEDELAI HITAM (Glycine soja (L.) Merr.) TERHADAP KADAR LDL TIKUS PUTIH (Rattus norvegicus)

Rizky, Putri Hapsari (2022) PENGARUH PEMBERIAN BUBUK KEDELAI HITAM (Glycine soja (L.) Merr.) TERHADAP KADAR LDL TIKUS PUTIH (Rattus norvegicus). Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Hypercholesterolemia is a condition of increased blood cholesterol accompanied by increased levels of Low-Density Lipoprotein (LDL). Increased levels cause an accumulation of fat on the artery walls which can lead to blockages in blood vessels. Anthocyanins in soybeans play a role in inhibiting the formation of cholesterol which will affect reducing LDL levels. The purpose of this study was to determine the effect of black soybean powder (Glycine soja (L.) Merr.) on LDL levels in white rats (Rattus norvegicus). This research is experimental with pretest and posttest controlled group design which is divided into control and treatment groups. In the pretest stage, all groups were given 2 ml of quail egg yolk in the morning and evening for 15 days. In the posttest stage, egg yolk was continued and black soybean powder was added at a dose of 0.80 g for 14 days in the treatment group. Measurements were using a photometer Clima MC 15. The results of the SPSS analysis on the Shapiro Wilk test showed the data were normally distributed at p>0.05 and the Paired T-Test test obtained a significance value of p<0.05 with a percentage decrease of 12.87% in the treatment group before and after. From the results of this study, it can be concluded that there is an effect of giving black soybean powder on LDL levels in white rats.

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