HUBUNGAN KADAR TIMBAL DALAM DARAH TERHADAP KADAR KREATININ DARAH PADA OPERATOR SPBU GOMBEL KOTA SEMARANG

Wahyu, Indah Perdana Putri (2022) HUBUNGAN KADAR TIMBAL DALAM DARAH TERHADAP KADAR KREATININ DARAH PADA OPERATOR SPBU GOMBEL KOTA SEMARANG. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Pb was found to be one of the ingredients used for fuel mixtures. Pb is a metal that has toxic properties to the human body can cause impaired functioning of the central nervous system, hematopetic. liver and kidneys. Pb that settles in the kidneys can cause disorders in the kidneys. Creatinine in the blood will increase and can poison cells in the body. The purpose of this study was to determine the relationship between lead levels in the blood and blood creatinine levels at the Gombel gas station operator in Semarang city. This type of research is observational analytic with a cross-sectional approach. The research sampling technique uses saturated sampling. The subjects of this study were 18 people at the Gombel gas station operator in Semarang city. Examination of Pb levels in the blood is carried out using the ICP-MS (Inductively Coupled Plasma-Mass Spectrometer) method, a wholeblood sample of 6 ml was taken using a trace element tube containing Na Heparin. Examination of blood creatinine levels using the Enzymeatic Colorimetric method. Samples in the form of serum as much as 3 ml were taken using a Clot Activator / SST tube. The hypothesis test was performed with the Spearman correlation test. The results showed that all respondents had Pb levels within the normal limit of <9μg / dL. Normal creatinine levels of 16 respondents. above normal as many as 2 respondents. The data after the Spearman correlation statistical test with p> 0.05 showed p = 0.700, then H0 was accepted so that there was no significant relationship between blood lead levels and blood creatinine levels in gas station operators.

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