FORMULASI DAN UJI AKTIVITAS SEDIAAN KRIM EKSTRAK ETANOL DAUN SUJI (Dracaena angustifolia Roxb.) TERHADAP PENYEMBUHAN LUKA SAYAT PADA TIKUS PUTIH JANTAN GALUR WISTAR

Damai, Rifi Riyani Cucu Randhika (2021) FORMULASI DAN UJI AKTIVITAS SEDIAAN KRIM EKSTRAK ETANOL DAUN SUJI (Dracaena angustifolia Roxb.) TERHADAP PENYEMBUHAN LUKA SAYAT PADA TIKUS PUTIH JANTAN GALUR WISTAR. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Ethanol extract of suji leaves (Dracaena angustifolia Roxb.) contains flavonoids that have the activity of healing wounds. This study was conducted by dividing test animals into 5 groups including positive control group (Betadin Cream 10%), negative control group, suji leaf cream extract group 4%, 6%, and 8%. The wound was administered using an incision wound method with a length of 2 cm, and a depth of ± 2mm each group smeared with cream ± 0.5 grams and conducted observations for 14 days. The research data was processed using statistics by ANOVA method with Tukey. The results of the reduction of the cut were processed using the One Way Anova Test and observed through the cut reduction chart. The statistical results show a p value of > 0.05 which means there is no statistically significant difference between F1, F2, F3, positive control and negative control. However on the chart showing the difference in the decrease in cuts, the highest graph was obtained on the administration of F3 with a concentration of suji leaf ethanol extract (Dracaena angustifolia Roxb.) of 8%.

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