UJI AKTIVITAS SEDIAAN GEL EKSTRAK ETANOL TANGKAI DAUN TALAS (Colocasia esculenta (L.) Schott) SEBAGAI OBAT LUKA BAKAR PADA TIKUS GALUR WISTAR

Hawa, Surya Marita (2021) UJI AKTIVITAS SEDIAAN GEL EKSTRAK ETANOL TANGKAI DAUN TALAS (Colocasia esculenta (L.) Schott) SEBAGAI OBAT LUKA BAKAR PADA TIKUS GALUR WISTAR. Other thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Burns are injuries that occur as a result of touching the body surface with objects that produce heat (fire, chemicals, electricity, or radiation) or substances that cause both strong acids and strong bases to contain phytochemicals contained in taro leaf stalks (Colocasia esculenta (L.) Schott) is able to help wound healing. The compound in taro leaf stalk (Colocasia esculenta (L.) Schott) was extracted using 70% ethanol as solvent. The study was conducted to divide the test animals into 5 groups including positive control (Bioplacenton Gel), negative control, group of 0.2 grams taro leaf stalk extract gel; 0.4 grams; and 0.6 grams. Burns were administered using heated metal with a diameter of 2 cm. Each group was smeared with ± 0.5 grams gel and carried out for 15 days. The results of the decrease in burn diameter were processed by statistical tests using the One Way ANOVA test with Tukey and observed through a burn reduction graph. Statistical results showed p value < 0.05 which means that there is a statistically significant difference between F1, F2, F3, positive control and negative control. The gel preparation of taro leaf stalk ethanol extract has the activity of burn wound healing and formula 3 has the best activity of burns wound healing.

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