UJI AKTIVITAS KOMBINASI EKSTRAK BAWANG PUTIH (Allium Sativum) DAN EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth.) SEBAGAI SENYAWA ANTIRADIKAL DPPH (1,1 diphenyl-2-Picrilhidrazyl)

Priskilla, Rachma Widya Putri (2017) UJI AKTIVITAS KOMBINASI EKSTRAK BAWANG PUTIH (Allium Sativum) DAN EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth.) SEBAGAI SENYAWA ANTIRADIKAL DPPH (1,1 diphenyl-2-Picrilhidrazyl). Diploma thesis, Sekolah Tinggi Ilmu Kesehatan Nasional.

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Abstract

Medical studies have shown that free radicals are involved in a variety of pathological processes. Most of the diseases begin with an excessive oxidation reaction in the body. The reactivity of free radicals can be inhibited by antioxidant systems. Antioxidants is an inhibitor used to inhibit autooxidation by scavenge free radicals and highly reactive molecules than damage cells will be inhibited. Plants that can be used as an compound antiradical is garlic and the leaves of marigolds have a flavonoid compounds that can be used as antioxidant. This study was conducted to determine antiradical DPPH (1,1 diphenyl-2- Picrilhidrazyl) activity of the combination of garlic extract and extract of leaves of marigolds in compotition 0: 1, 1: 0, 1: 2, and 2: 1. The methode extraction is done by maceration with 96% ethanol. The resultsof antiradical DPPH activity test showed that the combination has better than singular. The value of IC50 combination 1: 0 0: 1 1: 2 and 2: 1 are 101.7396 ppm, 47.4365 ppm, 34.5455 ppm, 42.1154 ppm, respectively.

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